P-DfMA Platform Design for Manufacture and Assembly

Universities organised into traditional silos are not providing the skills required for the change ahead such as scientists with coding and equipment knowledge, or engineers with scientific understanding.

key aspects of the implications o. f. economies of scale, it is simple compared to the actual complexities of decision making in the industry.Each product and portfolio and company is different.

What I find interesting.how production unit scale in some circumstances could have very significant impacts on financial returns.over the lifetime of a portfolio of products.

and where there appears to be little impact..It is also worth saying that the results have not been modelled where there are lower risk profiles than those of bringing new pharmaceutical products to market.. Let me start with a first curve.. M. odelled.

a scenario where the revenue value of the new products was very high.

you can see that scale has little relative influence over the NPV at different scales.Already impressive, we expect these metrics will only continue to improve over time.. Design to Value.

The starting point, and where we must begin in order to truly maximise the benefits that P-DfMA and MMC make possible, is to rework our core processes (design, procure, construct, operate) around a central, driving principle: process-led design.In other words, we must begin with the manufacture and assembly process in mind.

Innovation doesn’t respect discipline or sector boundaries.It needs to sit across the entire operation.